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South Africa Patient-Owned HIV/TB Research Cohort Retention Platform

COLD✧ v8health research / public healthaf16 Mar 2026

One-Liner

A WhatsApp-native patient portal for South African HIV and tuberculosis research cohorts that gives patients POPIA-compliant access to their own records (driving retention) while giving research program managers a real-time cohort-attrition dashboard — sold to institutions like the Desmond Tutu Health Foundation at $20-80K per cohort per year.

AI Thinking Process

T5: KwaMakhutha mobile-clinic patient has no digital record. POPIA §23 grants data-subject access rights but nobody productized patient-side POPIA records request for mobile clinic follow-up. 15-25% PrEP/HIV compliance drop-off from record gaps.

Verb Transplant: 'Data-subject request' (normal in GDPR/CCPA consumer privacy) transplanted into SA public-health records access. POPIA §23 WhatsApp-native PIN-authenticated records request.

G144 buyer-budget: NOT the patient (can't afford $2/mo). Public health system has no per-patient records budget. NGO revenue is unstable. G144 fires.

Kill reason (buyer) is POSITIONAL. Pivot: sell to HIV cohort study institutions (DTHF, HPRN, MSF SA) at $20-80K per cohort as patient-recruited longitudinal follow-up tool with data honorarium. Buyer has budget from grant funding.

Reborn as 'Patient-Owned Research Cohort Records for SA HIV/TB Studies.' Conviction 46% — marginal. Biggest worry: research procurement cycles 18-24 months gated by grant cycles.

POPIA §23 data-subject access cross-verified. HIV cohort attrition 25-45% cross-verified via published DTHF + HPRN studies.

REDCap is dominant and often free for academic non-profits. DTHF has in-house bespoke VMMC cohort tooling — suggests preference for custom builds. Ona.io could add patient-portal layer. Cohort.io European-based no SA presence.

Killed in deepening at 38% conviction. Research consortium buyer culture prefers grant-funded bespoke tools; 12-24 month procurement cycles gated by grant availability; DTHF's in-house-build preference signals the market will not procure productized SaaS at $20-80K scale.

Kill Reason

Research consortium buyer culture prefers grant-funded bespoke tooling over commercial SaaS. REDCap (Vanderbilt-hosted) is dominant in academic research and often free for the same non-profit institutions targeted. DTHF's history of building in-house bespoke tools for each study cohort (evidenced by their VMMC cohort tooling) suggests principal investigators do not perceive a $20-80K productized SaaS as solving their problem. Procurement cycle of 12-24 months gated by grant cycles is a structural commercial viability constraint. G144-adjacent buyer-budget structural mismatch: the buyer (PI/research institutions) is advocacy-aligned and has a strong preference for mission-funded tools over commercial SaaS.

Risk Analysis

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